MICROCLUSTERING: The Making Of A Myth (Part 3. What If They Existed? Chemical And Physiological Consequences)

MICROCLUSTERING: The Making Of A Myth (Part 3. What If They Existed? Chemical And Physiological Consequences)

PART 3. WHAT IF THEY EXISTED? CHEMICAL AND PHYSIOLOGICAL CONSEQUENCES POINTS TO CONSIDER Part 2 of the topic explained how all the evidence used to support microclustering is invalid. Here are a couple common sense ideas that refute the microclustering myth without all the technical science. COLLIGATIVE PROPERTIES ARE THE SAME If there really were a…

Bones

Bones

Li, J., et al., Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. BMC Musculoskelet Disord, 2017. 18(1): p. 58. Guo, J., et al., Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin. Int Orthop, 2017. 41(10): p. 2119-2128. Yamada, T., et al., Hydrogen supplementation of preservation solution improves…

Miscellaneous

Miscellaneous

Zhang, W., et al., Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. Biomedicine & Pharmacotherapy, 2018. 106: p. 1126-1134. Xu, F., et al., Hydrogen-Rich Saline Ameliorates Allergic Rhinitis by Reversing the Imbalance of Th1/Th2 and Up-Regulation of CD4+CD25+Foxp3+Regulatory T Cells, Interleukin-10, and Membrane-Bound Transforming Growth Factor-beta in Guinea…

Brain

Brain

Yuan, J., et al., Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. J Surg Res, 2018. 228: p. 238-246. Wu, X., et al., Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. Brain Res, 2018. Wang, H.,…

Cancer

Cancer

Yang, Y., Y. Zhu, and X. Xi, Anti‑inflammatory and antitumor action of hydrogen via reactive oxygen species. Oncology Letters, 2018. 16(3): p. 2771-2776. Wang, D., et al., Hydrogen gas inhibits lung cancer progression through targeting SMC3. Biomed Pharmacother, 2018. 104: p. 788-797. Jiang, Y., et al., Therapeutic efficacy of hydrogenrich saline alone and in combination with PI3K…

Lung and Other Organs

Lung and Other Organs

Zhang, G., et al., The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period. Transplantation, 2018. 102(8): p. 1253-1261. Wu, D., et al., Hydrogen protects against hyperoxia-induced apoptosis in type II alveolar epithelial cells via activation of PI3K/Akt/Foxo3a signaling pathway. Biochem Biophys Res Commun, 2018. 495(2): p. 1620-1627. Lu, W.,…

Liver

Liver

Li, H., et al., Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. Life Sci, 2018. 194: p. 7-14. Ishikawa, T., et al., Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study. Surg Today, 2018. Chen, M., et al., Hydrogen protects against liver injury…

Human Studies

Human Studies

Zhu, Q., et al., Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques. Sci Rep, 2018. 8(1): p. 8051. Nishimaki, K., et al., Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. Curr Alzheimer Res, 2018. 15(5): p. 482-492. Nakayama, M., et al., Novel haemodialysis…

Heart

Heart

Song, D., et al., Hydrogen rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats. Mol Med Rep, 2018. 18(2): p. 1925-1938. Matsuoka, H., et al., Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. Clin Exp Hypertens, 2018: p. 1-5 Feng, R., et al., Early Aerobic…

Hydrogen: An Emerging Medical Gas

Hydrogen: An Emerging Medical Gas

INTRODUCTION Molecular hydrogen (i.e. H2 gas) is gaining significant attention from academic researchers, medical doctors, and physicians around the world for its recently reported therapeutic potential [1]. One of the earliest publications on hydrogen as a medical gas was in 1975, by Dole and colleagues from Baylor University and Texas A&M [2]. They reported in the journal Science that…