Heart

Heart

Song, D., et al., Hydrogen rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats. Mol Med Rep, 2018. 18(2): p. 1925-1938. Matsuoka, H., et al., Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. Clin Exp Hypertens, 2018: p. 1-5 Feng, R., et al., Early Aerobic…

Hydrogen: An Emerging Medical Gas

Hydrogen: An Emerging Medical Gas

INTRODUCTION Molecular hydrogen (i.e. H2 gas) is gaining significant attention from academic researchers, medical doctors, and physicians around the world for its recently reported therapeutic potential [1]. One of the earliest publications on hydrogen as a medical gas was in 1975, by Dole and colleagues from Baylor University and Texas A&M [2]. They reported in the journal Science that…

Eye & Ear

Eye & Ear

Wu, J., et al., Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway. Biochem Biophys Res Commun, 2018. 495(4): p. 2462-2468. Ogawa, H., et al., Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen-rich saline in gerbil. Neurosci Lett, 2018. 665: p. 195-199. Tao, Y., et al., The Comparative Efficiency…

Calculating The Dose Of H2

Calculating The Dose Of H2

What Is “ppm”? The ppm is an acronym for “parts per million”, a unit of measure that describes how much of one substance (called the “solute”) is dissolved in a sample of water (called the “solvent”). This is a measurement of concentration (or density), which can often be helpful in our daily lives. The ppm…

Registered Clinical Studies

Registered Clinical Studies

Public Title Date of Registration   Effects of Hydronen Magnesium Tablets on Cardiometabolic Risk Factors and Inflammation in Subjects with Metabolic Syndrome. Hydrogen-rich Water for Non-alchoholic Fatty Liver DiseaseDouble blinded and placebo controlled examination to observe the effects of the water containing 7ppm molecular hydrogen on the gut microbiota. 2018   Open labeled examination to observe…

Kidney

Kidney

Nakayama, M., et al., Novel haemodialysis (HD) treatment employing molecular hydrogen (H2)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study. Sci Rep, 2018. 8(1): p. 254. Hosgood, S.A., et al., Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. Artif Organs, 2018. Cheng, T.C., et al., Nephroprotective effect of electrolyzed…

Ischemia/Reperfusion Injuries

Ischemia/Reperfusion Injuries

Liu, H., et al., Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion Hinjury. Mol Med Rep, 2015. 12(2): p. 2495-502. Huang, T., et al., Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle. J Surg Res, 2015. 194(2): p. 471-80. Zhou, L., et al., Beneficial effects of hydrogen-rich saline…

Hydrogen Chemistry/Physics

Hydrogen Chemistry/Physics

Kurokawa, R., et al., Convenient methods for ingestion of molecular hydrogen: drinking, injection, and inhalation. Med Gas Res, 2015. 5: p. 13. Akhavan, O., et al., Hydrogen-rich water for green reduction of graphene oxide suspensions. International Journal of Hydrogen Energy, 2015. 40(16): p. 5553-5560. Seo, T., R. Kurokawa, and B. Sato, A convenient method for determining the concentration of…

Hydrogen From Bacteria

Hydrogen From Bacteria

Liu, C., et al., Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes. Sci Rep, 2014. 4: p. 5485. Zhai, X., et al., Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. Free Radic Biol Med, 2013. 65: p. 731-41. Shimouchi,…

Hydrogen Review Articles

Hydrogen Review Articles

Zhang, Y., et al., Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside. Cell Physiol Biochem, 2018. 47(1): p. 1-10. Sano, M., et al., Promising novel therapy with hydrogen gas for emergency and critical care medicine. Acute Med Surg, 2018. 5(2): p. 113-118. Yoritaka, A., et al., Erratum to: A randomized double-blind multi-center trial of hydrogen…